• The blood metabolome of incident kidney cancer: A case-control study nested within the MetKid consortium 

      Guida, Florence; Tan, VY; Smith-Byrne, K; Alcala, Karine; Langenberg, C; Butterworth, AS; Surendran, P; Achaintre, David; Adamski, P; Bergmann, MM; Bull, CJ; Dahm, CC; Gicquiau, Audrey; Giles, GG; Gunter, MJ; Haller, T; Langhammer, Arnulf; Larose, TL; Ljungberd, B; Metspalu, A; Milne, RL; Muller, DC; Nøst, Therese Haugdahl; Sørgjerd, Elin Pettersen; Prehn, C; Riboli, E; Rinaldi, S; Rothwell, JA; Scalbert, A.; Severi, G; Sieri, S; Vermeulen, R; Vincent, EE; Waldenberger, M; Timpson, NJ; Johansson, M; Corbin, Laura J.; Stewart, Isobel D.; Amiano, Pilar; Schmidt, Julie A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-20)
    • Lung cancer risk discrimination of prediagnostic proteomics measurements compared with existing prediction tools 

      Feng, Xiaoshuang; Wu, Wendy Yi-Ying; Onwuka, Justina Ucheojor; Haider, Zahra; Alcala, Karine; Smith-Byrne, Karl; Zahed, Hana; Guida, Florence; Wang, Renwei; Bassett, Julie K.; Stevens, Victoria; Wang, Ying; Weinstein, Stephanie; Freedman, Neal D.; Chen, Chu; Tinker, Lesley; Nøst, Therese Haugdahl; Koh, Woon-Puay; Muller, David; Colorado-Yohar, Sandra M.; Tumino, Rosario; Hung, Rayjean J.; Amos, Christopher I.; Lin, Xihong; Zhang, Xuehong; Arslan, Alan A.; Sánchez, Maria-Jose; Sørgjerd, Elin Pettersen; Severi, Gianluca; Hveem, Kristian; Brennan, Paul; Langhammer, Arnulf; Milne, Roger L.; Yuan, Jian-Min; Melin, Beatrice; Johansson, Mikael; Robbins, Hilary A.; Johansson, Mattias (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-01)
      Background: We sought to develop a proteomics-based risk model for lung cancer and evaluate its risk-discriminatory performance in comparison with a smoking-based risk model (PLCOm2012) and a commercially available autoantibody biomarker test.<p><p>Methods: We designed a case-control study nested in 6 prospective cohorts, including 624 lung cancer participants who donated blood samples at most 3 ...
    • Systemic inflammation markers and cancer incidence in the UK Biobank 

      Nøst, Therese Haugdahl; Alcala, Karine; Urbarova, Ilona; Byrne, Karl Smith; Guida, Florence; Sandanger, Torkjel M; Johansson, Mattias (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-25)
      Systemic inflammation markers have been linked to increased cancer risk and mortality in a number of studies. However, few studies have estimated pre-diagnostic associations of systemic inflammation markers and cancer risk. Such markers could serve as biomarkers of cancer risk and aid in earlier identification of the disease. This study estimated associations between pre-diagnostic systemic inflammation ...